NEPHROTIC SYNDROME

NEPHROTIC SYNDROME

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Nephrotic Syndrome is a kidney disorder characterized by excessive protein loss in the urine, leading to low protein levels in the blood and swelling in various parts of the body. This condition results from damage to the glomeruli, which are small filtering units in the kidneys responsible for removing waste and excess fluids while retaining essential proteins. When the glomeruli are damaged, they allow proteins to leak into the urine, disrupting the body’s fluid balance and causing symptoms associated with Nephrotic Syndrome.

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Symptoms

Swelling (edema)

Swelling (edema)

Foamy urine

Weight gain

Causes

Nephrotic Syndrome can be caused by various conditions that damage the kidneys, particularly the glomeruli. Common causes include: Primary Kidney Diseases, such as minimal change disease, Focal Segmental Glomerulosclerosis (FSGS), and Membrane Nephropathy, directly affect kidney function.

Medicine
Medications
Certain drugs, including nonsteroidal anti-inflammatory drugs (NSAIDs) and some antibiotics, can potentially harm the kidneys.
Polycystic Kidney Disease (PKD)
Systemic Diseases
Conditions like diabetes, lupus, and amyloidosis, which affect multiple organs and can lead to kidney damage.
Infection
infections
Certain infections, such as hepatitis, HIV, and malaria, can contribute to kidney damage and nephrotic Syndrome.

Risk Factors

Factors that may increase the risk of developing Nephrotic Syndrome include

Chronic Diseases

Chronic Diseases

Diabetes, hypertension, and autoimmune diseases can increase the likelihood of kidney issues.
Infection

Infection

Viral infections, such as hepatitis B, hepatitis C, and HIV, are known risk factors.
Type of Inheritance

Genetic Predisposition

A family history of kidney diseases may raise the risk.